Peer-reviewed veterinary case report
Targeted NIR-II emissive nanoprobes for tumor detection in mice and rabbits.
- Journal:
- Chemical communications (Cambridge, England)
- Year:
- 2021
- Authors:
- Li, Yaxi et al.
- Affiliation:
- Department of Biomedical Engineering · China
Abstract
The functional NIR-II emissive nanoprobe loaded with AIEgen (cRGD-TTB NPs) achieved a high quantum yield (10.32%) and a high signal-to-background (S/B) ratio of 7.7 when employed for the visualization of large tumors (∼600 mm3) in rabbit models for the first time. This work will aid in the investigation of tumor targeting effect of therapeutic agents in large animal models.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34095919/