Peer-reviewed veterinary case report
Targeting multiple biofilm pathways.
- Journal:
- Chemistry & biology
- Year:
- 2009
- Authors:
- Hett, Erik C & Hung, Deborah T
- Affiliation:
- Department of Molecular Biology · United States
Abstract
Cegelski et al. (2009) demonstrate the importance of amyloid production for biofilm formation and host colonization using several mutant strains of pathogenic E. coli and small molecule inhibitors. This work reveals a path forward for studying the role of bacterial amyloids in vivo and suggests the potential for small molecules to target multiple biofilm formation pathways.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20064430/