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Peer-reviewed veterinary case report

Cat nasal cryptococcosis from temperature-sensitive Cryptococcus

By Bemis, D A et al.·Published in Journal of clinical microbiology·2000·Department of Comparative Medicine, United States·View original on PubMed

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Original publication title: Temperature-sensitive strain of Cryptococcus neoformans producing hyphal elements in a feline nasal granuloma.

Species:
cat

Plain-English summary

A cat with nasal problems was diagnosed with a fungal infection caused by a special strain of Cryptococcus neoformans, which is known to grow poorly at body temperature. The cat had a granuloma, which is a type of inflamed tissue, and tests showed both yeast cells and long hyphal structures in the affected area. This unusual strain was identified because it didn't grow well at the higher temperature typical of a cat's body. Treatment details weren't provided, but understanding the specific strain can help veterinarians choose the right approach for managing the infection.

People also search for: cat nasal infection treatment · Cryptococcus neoformans in cats · cat granuloma symptoms

Abstract

We report the isolation of a temperature-sensitive, serotype A, mating type alpha strain of Cryptococcus neoformans from a case of nasal cryptococcosis in a cat. The strain grew extremely slowly at 35 degrees C and failed to grow at 37 degrees C in vitro. Histopathological sections of the infected tissue revealed yeast cells producing hyphae up to several hundred micrometers in length, in addition to numerous encapsulated yeast cells typical of C. neoformans. The cultures grown on yeast extract-peptone-glucose agar at 35 degrees C also produced some yeast cells with germ tube-like hyphal elements up to 100 microm in length.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10655419/