Peer-reviewed veterinary case report
Terfenadine poisoning symptoms and treatment in dogs
By Otto, C M & Greentree, W F·Published in Journal of the American Veterinary Medical Association·1994·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Terfenadine toxicosis in dogs.
- Species:
- dog
Plain-English summary
A dog experienced poisoning after accidentally ingesting terfenadine, an antihistamine that can be harmful to pets. Symptoms of toxicity can occur even at low doses, and the dog required immediate veterinary care. The veterinarian induced vomiting and gave activated charcoal to help absorb the drug, along with supportive treatment to ensure the dog's recovery. With prompt action, the dog was able to recover from the effects of the poisoning.
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Abstract
Terfenadine is an antihistamine that has been reported to be safe for use in human beings and animals. This report focuses on an index case of terfenadine toxicosis and several cases of terfenadine toxicosis reported to the National Animal Poison Control Center from 1987 through 1992. Adverse effects of terfenadine can be seen with dosages as low as 6.6 mg/kg of body weight. Any accidental exposure to terfenadine should be treated by inducing emesis and by administering activated charcoal, along with supportive care.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7852152/