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Peer-reviewed veterinary case report

Dog skin granuloma treated successfully with tetracycline

By Rothstein, E et al.·Published in Journal of the American Animal Hospital Association·1997·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Tetracycline and niacinamide for the treatment of sterile pyogranuloma/granuloma syndrome in a dog.

Species:
dog

Plain-English summary

A 5-year-old mixed-breed dog was diagnosed with a skin condition called sterile pyogranuloma/granuloma syndrome, which caused lumps on the skin. Initially, the dog was treated with high doses of steroids, but when that stopped working, the vet switched to a combination of tetracycline and niacinamide, which are medications that can help reduce inflammation and fight infection. This new treatment worked well, leading to significant improvement in the dog's condition.

People also search for: dog skin lumps treatment · tetracycline for dogs · niacinamide for dog skin problems

Abstract

A sterile pyogranuloma/granuloma syndrome in a dog is described. Diagnosis was based on cytological examinations of the skin and lymph nodes and histopathological examinations of the skin and nictitans. Although the condition initially was responsive to large doses of glucocorticoids, it subsequently was treated successfully with tetracycline and niacinamide. The excellent responses of this dog suggest that this drug combination may be a viable therapeutic option for dogs in which glucocorticoids cannot be used.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9358425/