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Peer-reviewed veterinary case report

Thalamic pathways mediating motor and non-motor symptoms in a Parkinson's disease model.

Journal:
Trends in neurosciences
Year:
2023
Authors:
Xiao, Bin & Tan, Eng-King
Affiliation:
Department of Neurology

Abstract

In a recent study, Zhang, Roy, and colleagues have shown that neurons in the parafascicular (PF) thalamus project to three distinct neural structures in the basal ganglia. The neural circuits identified in the study were associated with specific motor and non-motor symptoms in a Parkinson's disease (PD) mouse model. The findings provide potential actionable therapeutic targets for this disease.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/36207171/