Peer-reviewed veterinary case report
Thalidomide treatment attenuates chemotherapy-induced gonadal toxicity.
- Journal:
- Fertility and sterility
- Year:
- 2011
- Authors:
- Ochalski, Melanie E et al.
- Affiliation:
- Department of Obstetrics · United States
Abstract
The aim of this study was to investigate gonadal-protective properties of thalidomide in a mouse model of chemotherapy-induced ovarian failure. Administration of thalidomide before alkylating chemotherapy preserved ovarian follicles and lead to the resumption of normal estrous cyclicity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20889152/