Peer-reviewed veterinary case report
How can custom-built mice help in veterinary research?
By Croy, B A·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2000·Department of Biomedical Sciences, Canada·View original on PubMed →
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Original publication title: The 1999 Reginald Thomson Lecture. Custom-built mice: unique discovery tools in biomedical research.
- Species:
- rodent
Plain-English summary
This research highlights the important role that mice play in understanding genetics and developing new treatments in medicine. Scientists use special techniques to create different types of mice that can help them learn more about diseases that affect both people and animals. By carefully choosing and breeding these mice, researchers can uncover valuable information that could improve health for both humans and pets. The study suggests that we should encourage more use of mice in veterinary research to help advance animal health.
Abstract
The study of mouse genetics is a science in its own right. Currently, the mouse is the central platform for model building in biomedical research. Recombinant DNA technology and mouse transgenesis have provided an almost unlimited resource of new animals that is constantly expanding. Investigators, through their selection of the most appropriate type of mouse and by imaginative combinations of animals in breeding or culture experiments, have the opportunity for discovery of new information that will benefit the health of both humans and species of veterinary interest. Wider appreciation and use of the mouse as a discovery tool in veterinary research should be encouraged.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10738597/