Peer-reviewed veterinary case report
Skin bacteria and fungi in healthy dogs and dogs with atopic
By Chermprapai, Suttiwee et al.·Published in Veterinary microbiology·2019·Department of Infectious Diseases and Immunology, Netherlands·View original on PubMed →
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Original publication title: The bacterial and fungal microbiome of the skin of healthy dogs and dogs with atopic dermatitis and the impact of topical antimicrobial therapy, an exploratory study.
- Species:
- dog
Plain-English summary
A group of dogs with atopic dermatitis (a skin allergy causing itching and inflammation) had their skin microbiomes studied before and after receiving topical antimicrobial treatment. The researchers found that both healthy dogs and those with atopic dermatitis had a variety of bacteria and fungi on their skin, with some common types present in both groups. After treatment, the diversity of these microbes increased in both healthy and affected dogs, suggesting that the topical therapy helped improve the skin's microbial balance. This could be beneficial for managing skin issues in dogs with allergies.
People also search for: dog skin allergy treatment · atopic dermatitis in dogs · topical antimicrobial for dog skin problems
Abstract
Canine atopic dermatitis is a genetically predisposed inflammatory and pruritic allergic skin disease that is often complicated by (secondary) bacterial and fungal (yeast) infections. High-throughput DNA sequencing was used to characterize the composition of the microbiome (bacteria and fungi) inhabiting specific sites of skin in healthy dogs and dogs with atopic dermatitis (AD) before and after topical antimicrobial treatment. Skin microbiome samples were collected from six healthy control dogs and three dogs spontaneously affected by AD by swabbing at (non-) predilection sites before, during and after treatment. Bacteria and fungi were profiled by Illumina sequencing of the 16S ribosomal RNA gene of bacteria (16S) and the internally transcribed spacer of the ribosomal gene cassette in fungi (ITS). The total cohort of dogs showed a high diversity of microbes on skin with a strong individual variability of both 16S and ITS profiles. The genera of Staphylococcus and Porphyromonas were dominantly present both on atopic and healthy skin and across all skin sites studied. In addition, bacterial and fungal alpha diversity were similar at the different skin sites. The topical antimicrobial treatment increased the diversity of bacterial and fungal compositions in course of time on both AD and healthy skin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30642603/