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Peer-reviewed veterinary case report

The complete mitochondrial genome for an epilepsy model of rat WAG/Rij strain (Rattus norvegicus).

Journal:
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis
Year:
2016
Authors:
Tian, Bu-Xian et al.
Affiliation:
a Department of Neurology · China
Species:
rodent

Abstract

Epilepsy is recurrent spontaneous seizures resulting from abnormal synchronized activity of neurons in the brain. Rodent models contributed significantly for the study of this disease. We sequenced the complete mitochondrial genome of an epilepsy model of rat WAG/Rij strain for the first time. The total length of the mitogenome was 16,310 bp and contains 159 SNPs compared with the Rattus norvegicus strain BN/SsNHsdMCW reference sequence.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25693714/