Peer-reviewed veterinary case report
The critical impact of sex on preclinical alcohol research - Insights from zebrafish.
- Journal:
- Frontiers in neuroendocrinology
- Year:
- 2022
- Authors:
- de Abreu, Murilo S et al.
- Affiliation:
- Moscow Institute of Physics and Technology
Abstract
Sex is an important biological variable that is widely recognized in studies of alcohol-related effects. Complementing clinical and preclinical rodent research, the zebrafish (Danio rerio) is the second most used laboratory species, and a powerful model organism in biomedicine. Like clinical and rodent models, zebrafish demonstrate overt sex differences in alcohol-related responses. Collectively, this evidence shows that the zebrafish becomes a sensitive model species to further probe in-depth sex differences commonly reported in alcohol research.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35810841/