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Peer-reviewed veterinary case report

The development of metastatic meningioma in a canine patient post-immunotherapy case report

Journal:
Frontiers in Veterinary Science
Year:
2026
Authors:
Mercy Paine et al.
Affiliation:
Department of Pathology and Population Medicine, College of Veterinary Medicine, Midwestern University, Glendale, AZ, United States · CH
Species:
dog

Abstract

Metastatic meningioma is a rare occurrence in canine patients, with only four previous cases reported. This case report examines a recurrent meningioma with pulmonary metastasis in a male Labradoodle that survived 28 months post clinical presentation. The meningioma recurred following surgery and treatment with an autologous tumor cell lysate vaccine. This case explores the potential role of immunotherapy, by extending survival time, creating conditions that allow for the rare development of metastatic disease.

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Original publication: https://doi.org/10.3389/fvets.2025.1646793