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Peer-reviewed veterinary case report

Dog developed metastatic brain tumor after immunotherapy treatment

By Mercy Paine et al.·Published in Frontiers in Veterinary Science·2026·Department of Pathology and Population Medicine, College of Veterinary Medicine, Midwestern University, Glendale, AZ, United States, CH·View original on DOAJ

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Original publication title: The development of metastatic meningioma in a canine patient post-immunotherapy case report

Species:
dog

Plain-English summary

A male Labradoodle was diagnosed with a rare type of brain tumor called meningioma, which came back after surgery and treatment with a special vaccine designed to help the immune system fight the cancer. Despite the recurrence and the tumor spreading to the lungs, the dog lived for 28 months after the initial diagnosis. This case highlights how immunotherapy can sometimes help extend a pet's life, even in challenging situations like metastatic cancer.

People also search for: dog brain tumor treatment · Labradoodle meningioma survival · immunotherapy for dog cancer

Abstract

Metastatic meningioma is a rare occurrence in canine patients, with only four previous cases reported. This case report examines a recurrent meningioma with pulmonary metastasis in a male Labradoodle that survived 28 months post clinical presentation. The meningioma recurred following surgery and treatment with an autologous tumor cell lysate vaccine. This case explores the potential role of immunotherapy, by extending survival time, creating conditions that allow for the rare development of metastatic disease.

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Original publication on DOAJ: https://doi.org/10.3389/fvets.2025.1646793