Peer-reviewed veterinary case report
Dog developed metastatic brain tumor after immunotherapy treatment
By Paine M et al.·2025·Department of Pathology and Population Medicine, United States·View original on Europe PMC →
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Original publication title: The development of metastatic meningioma in a canine patient post-immunotherapy case report.
- Species:
- dog
Plain-English summary
A male Labradoodle developed a rare type of brain tumor called meningioma, which came back after surgery and treatment with a special vaccine designed to help his immune system fight the cancer. Despite the recurrence and the tumor spreading to his lungs, he lived for 28 months after first showing symptoms. This case highlights how immunotherapy might help some dogs with cancer live longer, even when the disease becomes more complicated.
People also search for: dog brain tumor treatment · Labradoodle cancer survival · immunotherapy for dogs with cancer
Abstract
Metastatic meningioma is a rare occurrence in canine patients, with only four previous cases reported. This case report examines a recurrent meningioma with pulmonary metastasis in a male Labradoodle that survived 28 months post clinical presentation. The meningioma recurred following surgery and treatment with an autologous tumor cell lysate vaccine. This case explores the potential role of immunotherapy, by extending survival time, creating conditions that allow for the rare development of metastatic disease.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/41560863