Peer-reviewed veterinary case report
Blood test markers that help diagnose and predict parvovirus sepsis
By Varlik, Tuğba et al.·Published in Veterinary research communications·2025·Department of Internal Medicine·View original on PubMed →
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Original publication title: The diagnostic and prognostic utility of complete blood count (CBC)-derived indices in dogs with sepsis caused by canine parvoviral infection.
- Species:
- dog
Plain-English summary
A group of dogs with parvovirus infection, which can lead to severe illness, were studied to see how their blood tests could help diagnose and predict outcomes for those developing sepsis (a serious infection). The researchers found that certain blood parameters, like red blood cell and platelet counts, were significantly different in dogs with sepsis compared to healthy dogs. These blood tests showed strong potential for helping vets identify and manage sepsis in dogs more effectively. The findings suggest that using these blood indices could improve early detection and treatment strategies for affected dogs.
People also search for: dog parvovirus treatment · signs of sepsis in dogs · blood test results for dog infection
Abstract
This study aimed to evaluate the diagnostic and prognostic value of complete blood count (CBC)-derived indices incorporating red blood cell (RBC) and platelet (PLT) parameters in dogs that met the criteria for sepsis due to canine parvovirosis (CP). Fifty-two client-owned dogs with CP and ten healthy controls were enrolled in this study. CBC-derived indices, along with serum CRP and albumin concentrations, were evaluated before (T0) and after treatment (T1 and T3). Dogs meeting the criteria for sepsis exhibited statistically significantly higher RDW/L (P < 0.001), MCV/L (P < 0.001), MPV/L (P < 0.001), PLT/L (P < 0.001), PCT/L (P < 0.001), and PDW/L ratios (P < 0.001) compared to the control group. Receiver operating characteristic curve analysis revealed high diagnostic and prognostic performance for MCV/L (AUC: >0.949) and MPV/L (AUC: >0.961). In conclusion, CBC-derived indices incorporating RBC and PLT parameters can provide useful information about the diagnosis and prognosis in dogs with sepsis produced by parvovirus. These findings, if corroborated in larger studies, would support their integration into clinical practice to enhance the early detection and risk stratification in canine sepsis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41160228/