Peer-reviewed veterinary case report
Platelet-rich plasma injections for pain and lameness in dogs
By Cai, X L & Zaki, S·Published in Australian veterinary journal·2025·Sydney School of Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: The effect of intra-articular platelet-rich plasma injection on pain and lameness in dogs with osteoarthritis.
- Species:
- dog
Plain-English summary
A group of dogs with osteoarthritis (a painful joint condition) received either an injection of platelet-rich plasma (PRP) or a placebo to see if it would help reduce their pain and limping. While PRP is thought to help with inflammation and healing, the studies reviewed showed that there isn't strong evidence that it significantly improves pain or mobility compared to the placebo. More research is needed to determine how effective PRP really is for dogs with this condition.
People also search for: dog limping treatment · osteoarthritis in dogs · platelet-rich plasma for dog pain
Abstract
Osteoarthritis (OA) is a prevalent and progressive degenerative joint disease in dogs, leading to chronic pain, reduced mobility, and diminished quality of life. Conventional management strategies primarily aim to alleviate and palliate clinical signs of pain and reduced mobility. Platelet-rich plasma (PRP) is an emerging regenerative therapy that has gained interest for its potential disease modifying effects, through modulating inflammation and promoting tissue repair. This paper provides a critical appraisal of current literature on the effectiveness of intra-articular injection of PRP compared to a placebo on the clinical outcomes of lameness and pain in dogs with OA. Findings from 7 studies indicate that current evidence supporting the effectiveness of PRP in reducing pain and lameness is weak. Further research in the form of large, randomised, blinded controlled clinical trials is required to further assess the efficacy of PRP.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40692209/