The Effect of Mild Cyclic Loads on the Stress State of Degenerative Knee Joint Cartilages: A Numerical Study Aided by Experimental Data.

Abstract

<b>Background/Objectives</b>: This study investigates the effect of mild cyclic loads on the stress state of degenerative knee joint cartilages using a combination of experimental data and numerical modeling. <b>Methods</b>: A three-dimensional finite element model of the knee joint was developed based on CT scans, incorporating key components such as the femur, tibia, cartilage layers, and meniscus. Special attention was given to the mechanical properties of cartilages, which were determined through high-sensitivity dynamometer tests of cartilage samples. The experimentally obtained force-displacement curves for cartilage samples affected by third-degree gonarthrosis were integrated into the numerical model. This allowed for an in-depth investigation of the interactions between neighboring tissues of the knee joint under cyclic loading and unloading conditions. <b>Results</b>: Experimental data revealed nonlinear mechanical behavior of cartilage under loading and unloading conditions, characterized by an elastic hysteresis loop. Experimental results demonstrated that degenerated cartilage, under small stresses (up to 0.13 MPa), retains an elastic hysteresis behavior. The numerical simulation provided insights into the stress distribution within the knee joint components, revealing that even in cases of cartilage degeneration, as long as its structural integrity is maintained, mild loads do not cause sufficient stress concentrators, while the longitudinal tears in the same conditions cause the increment of stress values up to 20%. <b>Conclusions</b>: Findings contribute to a better understanding of the mechanical response of degenerative cartilage and offer valuable guidance for the development of therapeutic and rehabilitation strategies for patients with degenerative tissue diseases.