Peer-reviewed veterinary case report
The effect of toll-like receptor 4 on macrophage cytokines during endotoxin induced uveitis.
- Journal:
- International journal of molecular sciences
- Year:
- 2012
- Authors:
- Yang, Shuo et al.
- Affiliation:
- Department of Ophthalmology · China
- Species:
- rodent
Abstract
Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 in vivo during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation in vitro to elucidate the effect of TLR4 on cytokines during EIU.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22837708/