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Peer-reviewed veterinary case report

Water and shampoo do not reduce fluralaner flea and tick protection

By Taenzler, Janina et al.·Published in Parasites & vectors·2016·MSD Animal Health Innovation GmbH, Germany·View original on PubMed

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Original publication title: The effect of water and shampooing on the efficacy of fluralaner spot-on solution against Ixodes ricinus and Ctenocephalides felis infestations in dogs.

Species:
dog

Plain-English summary

A group of 32 Beagle dogs received a topical flea and tick treatment called fluralaner (Bravecto) to see if bathing or water immersion afterward would affect its effectiveness. The dogs were either shampooed or immersed in water a few days after treatment, but both groups still showed nearly 100% effectiveness against fleas and ticks for the entire 12 weeks. This means that pet owners can confidently bathe their dogs after applying this treatment without worrying about it losing effectiveness.

People also search for: dog flea treatment effectiveness · can I bathe my dog after flea treatment · Bravecto shampooing effects

Abstract

BACKGROUND: Fluralaner spot-on solution provides immediate and persistent efficacy against tick and flea infestations in dogs and cats for 12-weeks following topical administration. The active ingredient fluralaner is distributed systemically following transdermal absorption. Therefore, this study tested the hypothesis whether water-immersion or shampooing of dogs following administration of fluralaner spot-on solution has an impact on subsequent tick and flea efficacy. METHODS: Thirty-two Beagle dogs were allocated to four study groups of 8 dogs each. On day 0, dogs in the 2 treatment groups received topical administration of fluralaner (Bravecto&#x2122; spot-on solution) according to label instructions. Dogs in the 2 corresponding control groups remained untreated. On days 3, 21, 49, and 77 dogs in one treatment group and control group were water-immersed for 2-5&#xa0;min, while dogs in the other treatment group and control group were shampooed 6-8&#xa0;min with a commercial foaming micro-emulsion, unscented product. On days 4, 28, 56, and 84 all dogs were co-infested with 50&#x2009;&#xb1;&#x2009;2 female and 10&#x2009;&#xb1;&#x2009;2 male Ixodes ricinus and 100&#x2009;&#xb1;&#x2009;4 Ctenocephalides felis, with tick and flea removal and counts 48&#x2009;&#xb1;&#x2009;2&#xa0;h post-infestation. Efficacy against ticks and fleas was calculated for each assessment time point. RESULTS: No treatment-related adverse event was observed in any of the 16 dogs treated with fluralaner spot-on solution during the study. Efficacy against ticks at each assessment time point was between 99.7 and 100&#xa0;% in the water-immersed group and between 99.2 and 100&#xa0;% in the shampooed group. Efficacy against fleas was 100&#xa0;% at each assessment time point as well in the water-immersed as the shampooed group. Tick and flea reduction in both treatment groups was significant at all assessment time points (p&#x2009;<&#x2009;0.0001). CONCLUSIONS: Neither water-immersion nor shampooing after single topical administration of fluralaner spot-on solution had an impact on the excellent tick and flea efficacy over the 12-week recommended re-treatment interval.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27241021/