Peer-reviewed veterinary case report
How well antibiotics treat dog skin infections like pyoderma
By Summers, Jennifer F et al.·Published in Veterinary dermatology·2012·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: The effectiveness of systemic antimicrobial treatment in canine superficial and deep pyoderma: a systematic review.
- Species:
- dog
Plain-English summary
A study found that dogs with skin infections called pyoderma (which can be either superficial or deep) responded well to certain antibiotics. For superficial pyoderma, an injection of cefovecin was highly effective, while deep pyoderma showed good results with oral amoxicillin-clavulanic acid. Other antibiotics like clindamycin and trimethoprim-sulphamethoxazole also helped with superficial cases. However, some dogs experienced side effects from the treatments, and a few had to stop due to severe reactions. Overall, these findings suggest that specific antibiotics can effectively treat pyoderma in dogs, but more research is needed to refine treatment options.
People also search for: dog skin infection treatment · antibiotics for dog pyoderma · cefovecin for dogs skin problems
Abstract
AIM: To identify and evaluate existing evidence for the effectiveness of systemic antimicrobial treatments for naturally occurring superficial and deep canine pyoderma. METHOD: Electronic searches of PubMed, MEDLINE and CAB Direct were carried out (25 May 2011) without date or language restrictions. Proceedings of ESVD/ECVD, AAVD/ACVD, NAVDF and WCVD annual congresses were searched. Unpublished studies were sought via the Veterinary Dermatology discussion list and Veterinary Information Network. RESULTS: Seventeen full-length, peer-reviewed controlled trials reporting clinical outcomes of systemic antimicrobial treatment for canine pyoderma were identified. Outcomes specific to superficial or deep pyoderma were reported in nine and five studies, respectively. Five studies reported outcomes only for nondifferentiated pyoderma depth. Heterogeneity of study designs and outcome measures made meta-analysis inappropriate. A good level of evidence was identified supporting the high efficacy of subcutaneously injected cefovecin in superficial pyoderma and for oral amoxicillin-clavulanic acid in deep pyoderma. A fair level of evidence was identified for moderate to high efficacy of oral amoxicillin-clavulanic acid, clindamycin, cefadroxil, trimethoprim-sulphamethoxazole and sulfadimethoxine-ormetoprim in superficial pyoderma and oral pradofloxacin, oral cefadroxil and subcutaneously injected cefovecin in deep pyoderma. Eleven trials reported observations of adverse effects in treated pyoderma cases by intervention group; four dogs were withdrawn owing to the severity of adverse effects. CONCLUSIONS: There is a need for greater numbers of adequately sized, blinded, randomized controlled trials evaluating systemic antimicrobial interventions for canine pyoderma. Improved differentiation between superficial and deep pyoderma in outcome reporting, outcome measure standardization and association of outcomes with causative bacterial species and their resistance patterns are required.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22734856/