Peer-reviewed veterinary case report
Clomipramine treatment does not improve hair loss in cats
By Mertens, Petra A et al.·Published in Journal of the American Animal Hospital Association·2006·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: The effects of clomipramine hydrochloride in cats with psychogenic alopecia: a prospective study.
- Species:
- cat
Plain-English summary
A group of cats with excessive grooming and hair loss, known as psychogenic alopecia, were treated with a medication called clomipramine to see if it would help them regrow their fur. After 56 days, the results showed that the medication did not significantly improve their grooming habits or hair regrowth compared to those receiving a placebo. This means that clomipramine might not be effective for this condition, but it's unclear if the treatment duration or the number of cats involved played a role in these results.
People also search for: cat hair loss treatment · clomipramine for cats · why is my cat over-grooming
Abstract
A double-blind, placebo-controlled clinical trial was conducted to determine the efficacy of clomipramine hydrochloride in cats with psychogenic alopecia. Twenty-five cats were randomly assigned to receive clomipramine hydrochloride (0.5 mg/kg orally q 24 hours) or placebo for 56 days. Eleven cats in each group completed the trial. The results of this study showed that clomipramine hydrochloride failed to demonstrate significant changes in the number of grooming bouts, hair regrowth, and the area of alopecia in cats with psychogenic alopecia when compared to a placebo. It was uncertain whether these results reflected a lack of drug efficacy, insufficient treatment duration, or an insufficient number of cases enrolled.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16960036/