Peer-reviewed veterinary case report
Using optical coherence tomography to check front eye inflammation
By Jeong, Youngseok et al.·Published in Veterinary ophthalmology·2022·Department of Veterinary Clinical Sciences, South Korea·View original on PubMed →
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Original publication title: The feasibility of clinical evaluation for anterior uveitis through spectral-domain optical coherence tomography in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with anterior uveitis (inflammation of the front part of the eye) underwent advanced eye imaging using a technique called spectral-domain optical coherence tomography (SD-OCT) to help assess their condition. The study found that SD-OCT could effectively measure eye inflammation and other important factors, such as the number of inflammatory cells and the thickness of the cornea. This imaging method showed a strong correlation with traditional eye exams, suggesting it could be a helpful tool for veterinarians in diagnosing and monitoring anterior uveitis in dogs. Overall, SD-OCT may enhance the evaluation process for dogs suffering from this eye condition.
People also search for: dog eye inflammation treatment · anterior uveitis in dogs · SD-OCT for dogs eye problems
Abstract
OBJECTIVE: To evaluate the clinical application of spectral-domain optical coherence tomography (SD-OCT) for anterior uveitis in dogs. Animals and procedures Client-owned dogs presenting with anterior uveitis and clinically healthy dogs were enrolled in this study. Included eyes were divided into 5 groups by flare grade and 3 groups by cell grade through slit-lamp biomicroscopy. Each eye was examined using SD-OCT following slit-lamp biomicroscopy. The ratio of aqueous signal intensity to air signal intensity, which is called the aqueous-to-air relative intensity (ARI) index, was used to evaluate the flare grade. Cell number, central corneal thickness (CCT), and the presence of keratic precipitates (KPs) were analyzed on SD-OCT. The OCT parameters, including ARI index, cell number, and CCT, were compared to the slit-lamp clinical flare and cell grade. RESULTS: Thirty-six eyes with anterior uveitis and 27 healthy eyes were enrolled. The ARI index showed a significant correlation with clinical flare grade (r = 0.811, p < .001). In multiple regression analysis, the ARI index and CCT showed a significant negative correlation (r = -0.258, p = .044). The number of cells on SD-OCT significantly increased with cell grade on slit-lamp biomicroscopy (r = 0.653, p < .001). The clinical flare grade and CCT were significantly correlated in the partial correlation analysis after controlling for age (partial correlation coefficient = 0.471, p = .002). KPs were observed in 61% of the eyes with flare using SD-OCT (22/36 eyes). CONCLUSIONS: Spectral-domain optical coherence tomography could provide quantitative information, including the ARI index, cell counts, and CCT in dogs. SD-OCT is an auxiliary modality for slit-lamp biomicroscopy when evaluating anterior uveitis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34793607/