Peer-reviewed veterinary case report
The first case of Tyzzer's disease in a young foal in Italy: a case report.
- Journal:
- Veterinaria italiana
- Year:
- 2021
- Authors:
- Ellero, Nicola et al.
- Affiliation:
- Departement of Veterinary Medical Sciences University of Bologna. nicola.ellero3@unibo.it. · Italy
- Species:
- horse
Plain-English summary
A one-month-old foal in Italy became very sick and sadly passed away after showing signs of being very tired, having a fever, and not eating. After the foal was examined, it was found to have severe yellowing of the skin and liver damage. Tests showed that the foal had Tyzzer's disease, which is caused by a bacteria called Clostridium piliforme that affects the liver. This case is notable because it is the first time this type of liver disease has been reported in a horse in Italy. Unfortunately, despite the efforts to treat the foal, it did not survive.
Abstract
Seizures, coma and death rapidly appeared after admission in a one ‑month‑old foal with a history of lethargy, fever and anorexia. Severe icterus and necrotizing hepatitis were observed at necropsy. Clinical signs, laboratory and postmortem findings were compatible with a suspect of clostridial hepatitis. Tyzzer’s disease was confirmed by the presence of organisms morphologically consistent with Clostridium piliforme in the hepatocytes at the margins of multiple areas of hepatic necrosis. To the authors’ knowledge, this is the first reported case of clostridial hepatitis caused by Clostridium piliforme in a horse in Italy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34971513/