Peer-reviewed veterinary case report
Terbinafine-resistant Microsporum canis infection in a cat
By Hsiao, Yun-Hsia et al.·Published in The Journal of veterinary medical science·2018·Asian Veterinary Specialist Referral Center·View original on PubMed →
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Original publication title: The first report of terbinafine resistance Microsporum canis from a cat.
- Species:
- dog
Plain-English summary
A 2-year-old exotic shorthair cat was brought in with bald patches and mild scaling on its body, which turned out to be a fungal infection called Microsporum canis. Tests confirmed the infection, and it was found that the fungus was resistant to terbinafine, a common antifungal medication. However, the cat responded well to treatment with itraconazole, another antifungal, and was cured of the infection.
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Abstract
A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood's lamp and trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent with M. canis. Dermatophyte test medium (DTM) and polymerase chain reaction (PCR) were used for identification. E-test and broth microdilution test were then utilized to estimate antifungal minimal inhibitory concentrations (MICs) towards ITZ and TRF respectively. The strain was isolated from the patient and revealed TRF MIC >32 µg/ml and ITZ MIC 0.023 µg/ml. Patient was cured of dermatophytosis with systemic ITZ.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29657238/