Peer-reviewed veterinary case report
The full genome sequences of 8 equine herpesvirus type 4 isolates from horses in Japan.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2017
- Authors:
- Izume, Satoko et al.
- Affiliation:
- Department of Applied Veterinary Sciences · Japan
- Species:
- horse
Abstract
Equine herpesvirus type 4 (EHV-4) is one of the most important pathogens in horses. To clarify the key genes of the EHV-4 genome that cause abortion in female horses, we determined the whole genome sequences of a laboratory strain and 7 Japanese EHV-4 isolates that were isolated from 2 aborted fetuses and nasal swabs of 5 horses with respiratory disease. The full genome sequences and predicted amino acid sequences of each gene of these isolates were compared with of the reference EHV-4 strain NS80567 and Australian isolates that were reported in 2015. The EHV-4 isolates clustered in 2 groups which did not reflect their pathogenicity. A comparison of the predicted amino acid sequences of the genes did not reveal any genes that were associated with EHV-4-induced abortion.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27840393/