Peer-reviewed veterinary case report
The genetic and epigenetic landscape for CNS drug discovery targeting cross-diagnostic behavioral domains.
- Journal:
- European journal of pharmacology
- Year:
- 2015
- Authors:
- de Mooij-van Malsen, Annetrude J G et al.
- Affiliation:
- Department of Translational Neuroscience · Germany
Abstract
Animal studies play a central role in the identification and testing of novel drugs for CNS disorders. In his longstanding career, Berend Olivier has significantly contributed to CNS drug discovery by applying and supporting novel views and methodologies in the fields of behavioral neuroscience, pharmacology, and (epi-) genetics. Here we review and put forward some of these integrated approaches that have led to a productive collaboration and new insights into the genetic and epigenetic regulation of neurobehavioural traits related to psychiatric disorders.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25107283/