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Peer-reviewed veterinary case report

Bovine coronavirus can infect 1-month-old puppies without symptoms

By Kaneshima, Takashi et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Infectious Disease, Japan·View original on PubMed

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Original publication title: The infectivity and pathogenicity of a group 2 bovine coronavirus in pups.

Species:
dog
Breathing & coughDogs

Plain-English summary

Three 1-month-old puppies were exposed to a type of bovine coronavirus (BCoV) to see if it could infect them. While the virus did infect the puppies, as shown by the presence of antibodies and viral genes in their samples, none of the puppies showed any signs of illness like coughing or diarrhea. This suggests that while BCoV can infect dogs, it may not cause any noticeable symptoms in young pups.

People also search for: puppy coronavirus symptoms · bovine coronavirus in dogs · dog respiratory infection treatment

Abstract

Canine respiratory coronavirus (CRCoV), which is more closely related to the bovine coronavirus (BCoV), has recently been detected in dogs. In this study, we examined whether BCoV was capable of infecting and exhibiting pathogenicity in dogs. Three 1-month-old pups were oronasally given field isolates of BCoV, and were kept together with 2 control animals. As a result, increases in BCoV-neutralizing antibody titers were confirmed in all pups in the challenged and control groups. Moreover, the virus gene was also detected in oral and rectal swabs by RT-PCR. These results indicate that BCoV infects dogs, and easily infects other dogs that are kept together. However, no clinical symptoms such as respiratory symptoms and diarrhea were observed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17409649/