Peer-reviewed veterinary case report
The lipopolysaccharide core of Actinobacillus suis and its relationship to those of Actinobacillus pleuropneumoniae.
- Journal:
- Biochemistry and cell biology = Biochimie et biologie cellulaire
- Year:
- 2011
- Authors:
- Ganeshapillai, Jeyabarathy et al.
- Affiliation:
- Department of Chemistry · Canada
Abstract
The Gram-negative bacteria Actinobacillus suis colonizes the upper respiratory and genital tracts of swine. Along with capsular polysaccharides, lipopolysaccharides (O-chain→core→lipid A~cell) are a main cell-surface component of A. suis. In this study, we determined that A. suis lipopolysaccharide incorporates a conserved core that shares some structural features with several core types of A. pleuropneumoniae . These common core structural features likely account for the observed serological cross-reactivity between A. suis and A. pleuropneumoniae, and the data suggest that the structural epitopes responsible for immunogenicity are those in the outer core domain.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21639829/