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Peer-reviewed veterinary case report

The lymphopenic mouse in immunology: from patron to pariah.

Journal:
Immunity
Year:
2006
Authors:
Singh, Nevil J & Schwartz, Ronald H
Affiliation:
National Institute of Allergy and Infectious Diseases (NIAID) · United States

Abstract

A recent surge of interest in the behavior of T and B cells in lymphopenic model systems has resurrected a certain cynicism about the validity of using such models to answer important immunological questions. Here we discuss this skepticism in a broader historical context.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17174925/