Peer-reviewed veterinary case report
The Mouse Aortocaval Fistula Model with Intraluminal Drug Delivery.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2018
- Authors:
- Isaji, Toshihiko & Dardik, Alan
- Affiliation:
- Yale School of Medicine · United States
Abstract
The arteriovenous fistula (AVF) is the most common type of vascular access currently used for hemodialysis, but long-term outcomes remain poor in many patients; understanding the basic mechanisms of venous remodeling within the fistula environment is critical to improve our understanding of AVF maturation. In this chapter, we describe a method to create a murine aortocaval fistula that allows intraluminal drug delivery. This model reliably recapitulates human AVF maturation and therefore is a good consideration to study venous remodeling.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29987827/