Peer-reviewed veterinary case report
How diet and gut bacteria affect inflammatory bowel disease in dogs
By Soufien Rhimi et al.·Published in Metabolites·2022·Microbiota Interaction with Human and Animal Team (MIHA), Micalis Institute, AgroParisTech, Université Paris-Saclay, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, 78350 Jouy-en-Josas, France, CH·View original on DOAJ →
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Original publication title: The Nexus of Diet, Gut Microbiota and Inflammatory Bowel Diseases in Dogs
- Species:
- dog
Plain-English summary
Veterinary researchers are looking closely at inflammatory bowel diseases (IBD) in dogs, which are serious conditions affecting their digestive system. While we don't yet know exactly what causes these diseases, it's thought that a mix of factors, including diet, the immune system in the intestines, and the bacteria living in the gut, all play a role. Recent studies suggest that what dogs eat can significantly affect the types of bacteria in their gut, which in turn can influence their health and how these diseases develop. Understanding how diet interacts with gut health is important for creating better feeding guidelines and potential new treatments for dogs suffering from IBD. Overall, this research highlights the importance of diet in managing these complex health issues in dogs.
Abstract
Canine inflammatory bowel diseases (IBD) are of increasing interest in veterinary medicine. They refer to complex and debilitating conditions of dogs’ gastrointestinal tract. Although little evidence for causal inferences is currently available, it is believed that IBD pathophysiology entails intricate interactions between environmental factors, the intestinal immune system, and the microbial communities that colonize the gut. To better understand the mechanisms underlying these disorders, leveraging factors associated with the development of these diseases is imperative. Of these factors, emerging evidence supports the role of dietary patterns as key players influencing the composition and function of gut microbes, with subsequent effects on health and disease. In this review, we particularly focus on addressing IBD in dogs and discuss how specific nutrients may elicit or relieve gut inflammation. Gaining mechanistic insights into such interplay and the underpinning mechanisms is key to inferring dietary recommendations, and setting up new and promising therapeutics.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/metabo12121176