Peer-reviewed veterinary case report
Eye pressure rise then normal after steroid injection in dogs
By Molleda, José M et al.·Published in Veterinary journal (London, England : 1997)·2008·Department of Animal Medicine and Surgery, Spain·View original on PubMed →
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Original publication title: The ocular effects of intravitreal triamcinolone acetonide in dogs.
- Species:
- dog
Plain-English summary
A group of healthy dogs received an injection of a medication called triamcinolone acetonide in one eye to see how it affected their eyes. After the injection, all the dogs experienced a temporary increase in eye pressure, but it returned to normal within about 12 minutes. The most common side effect noticed was redness in the eye. The medication was still present in the eyes during follow-up exams, with some dogs showing tiny crystals even after 90 days. Overall, the injection was safe and effective for treating eye conditions in dogs.
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Abstract
The aim of the study was to determine the ocular safety of a single intravitreal dose of triamcinolone acetonide (IVTA) in dogs. Eleven healthy dogs received a single IVTA injection (8 mg) through the mid-temporal pars-plana of the left eye (OS) using a 27G needle. The dogs were re-evaluated immediately post-IVTA, every 5 min until pre-IVTA values had returned, then daily for 3 days, weekly for 1 month and monthly for 3 months. Immediately post-IVTA, all the treated eyes showed a rise in intraocular pressure (IOP) with a mean value of 41.8+/-8.9 mm Hg. The IOP values then decreased progressively to 14.5+/-2.1 mm Hg at 12.2+/-3.8 min post-IVTA. From then on, normal IOP values were maintained throughout the 3-month monitoring period. The most frequently observed clinical sign post-IVTA was conjunctival hyperaemia. The presence of triamcinolone acetonide in the vitreous was observed in all subsequent examinations of 10/11 eyes and there were still triamcinolone crystals in 5/11 eyes after 90 days. It was concluded that intravitreal injection of triamcinolone acetonide in dogs is feasible under sedation. The immediate increase in IOP post-IVTA is short-lived and pressure quickly returns to pre-IVTA levels.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17466546/