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Peer-reviewed veterinary case report

The Path to Diagnosis: Best Practices in Gastrointestinal Histopathology Collection and Examination.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2026
Authors:
Giaretta, Paula R
Affiliation:
Department of Small Animal Clinical Sciences · United States

Abstract

This article emphasizes the importance of strategic gastrointestinal biopsy collection, handling, and interpretation in dogs and cats. It highlights the need for high-quality, well-oriented samples, proper fixation, and detailed submission forms to ensure accurate diagnosis of inflammatory, neoplastic, and infectious diseases. The review discusses techniques for endoscopic biopsies, histopathologic evaluation, and ancillary testing, including immunohistochemistry and special stains. Proper communication among clinicians, histotechnologists, and pathologists is crucial for reliable results. Overall, optimized biopsy procedures and collaboration are essential for precise diagnosis, guiding effective treatment and improving patient outcomes in veterinary gastrointestinal medicine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41763982/