Peer-reviewed veterinary case report
Pain relief after spay surgery in dogs using morphine or fentanyl
By Pekcan, Zeynep & Koc, BahattinĀ·Published in Veterinary anaesthesia and analgesiaĀ·2010Ā·Department of SurgeryĀ·View original on PubMed ā
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Original publication title: The post-operative analgesic effects of epidurally administered morphine and transdermal fentanyl patch after ovariohysterectomy in dogs.
- Species:
- dog
Plain-English summary
Twenty female dogs were given either an epidural morphine injection or a transdermal fentanyl patch after they had surgery to remove their ovaries and uterus. The dogs that received the epidural morphine experienced less pain and were calmer compared to those with the fentanyl patch, who showed signs of discomfort and vocalization. Additionally, the fentanyl patch group had more side effects, such as increased salivation and loss of appetite, which lasted longer than in the morphine group. Overall, the study found that epidural morphine was more effective for pain relief and had fewer negative side effects after surgery.
People also search for: dog surgery pain relief options Ā· epidural morphine for dogs Ā· fentanyl patch side effects in dogs
Abstract
OBJECTIVE: To investigate the analgesic and side effects of epidural morphine or a fentanyl patch after ovariohysterectomy in dogs. STUDY DESIGN: Prospective, randomized clinical study. ANIMALS: Twenty female mongrel dogs undergoing ovariohysterectomy. METHODS: The dogs were allocated to one of two groups: epidural morphine or transdermal fentanyl patch. Anaesthesia was induced with propofol and maintained with isoflurane. Morphine (0.1 mg kg(-1)) was administered epidurally in the epidural morphine group and a transdermal fentanyl patch was applied 24 hours before the operation in the fentanyl patch group. The heart rate, respiratory rate, body temperature, plasma cortisol concentration, and sedation and analgesia scores were recorded during the 24 hour post-operative period. Adverse effects such as vomiting, anorexia, skin reactions, urinary retention, and time to start licking the surgical site were also recorded. p<0.05 was considered significant. Statistical analyses utilized anova for repeated measures, Friedman tests, Mann-Whitney U-tests and independent sample t-tests as relevant. RESULTS: Pain scores were lower in the epidural group than in the fentanyl group at all post-operative times. The dogs in the epidural morphine group were calm and relaxed, whereas discomfort and vocalization were recorded in the fentanyl patch group. The sedation scores were higher in the fentanyl patch group throughout the 12 hour period. Salivation and anorexia lasted longer in the fentanyl patch group than in the epidural morphine group. Plasma cortisol concentrations were high in the early post-operative period in both groups. The fentanyl patch group had higher cortisol concentrations than the epidural morphine group. Slight erythema was recorded in two dogs when the patches were removed. CONCLUSION AND CLINICAL RELEVANCE: Epidurally administered morphine provided better analgesia and caused fewer adverse effects than the fentanyl patch after ovariohysterectomy in dogs.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21040380/