Peer-reviewed veterinary case report
The presentation of haptenated proteins and activation of T cells in the mesenteric lymph nodes by dendritic cells in the TNBS colitis rat.
- Journal:
- Annals of the New York Academy of Sciences
- Year:
- 2004
- Authors:
- Ishiguro, Yoh et al.
- Affiliation:
- First Department of Internal medicine · Japan
- Species:
- rodent
Abstract
We described the role of dendritic cells (DCs) in aspects of T cell activation at the mesenteric lymph nodes (MLN) in trinitrobenzene sulfonic acid (TNBS)-induced colitis. An antigenic-immune response is induced at the MLN, and dendritic cells are the affected cell type. Cross-linking and GRO/CINC-1 have synergistic effects for DC maturation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15681777/