Peer-reviewed veterinary case report
Bacterial infections in dogs during cyclosporine treatment rates
By High, Endya J & Olivry, Thierry·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2020·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: The prevalence of bacterial infections during cyclosporine therapy in dogs: A critically appraised topic.
- Species:
- dog
Plain-English summary
A group of dogs with skin allergies, specifically atopic dermatitis, were treated with cyclosporine, a medication that helps manage their condition. During the treatment, about 11% of these dogs developed bacterial infections, mostly affecting their skin and urinary systems. In another group of dogs receiving higher doses of cyclosporine for other health issues, the infection rate rose to 17%, with infections occurring in the gastrointestinal, urinary, and respiratory systems. Overall, while bacterial infections can happen during cyclosporine therapy, they are more common when the medication is used for immune suppression rather than for allergies.
People also search for: dog skin infection cyclosporine · atopic dermatitis treatment in dogs · bacterial infections in dogs on immunosuppressants
Abstract
Cyclosporine is used to treat immune-mediated and allergic conditions and to prevent transplant rejection. To determine the prevalence of bacterial infections during cyclosporine therapy in dogs, 2 databases were searched and 14 articles reporting usable data were identified. In 828 dogs with atopic dermatitis receiving anti-allergic dosages of cyclosporine, the prevalence of bacterial infections was 11%; these occurred most often in the integument and urinary systems and not in multiple systems. In 95 dogs receiving cyclosporine at higher dosages for other conditions, the prevalence of bacterial infection was 17%, and these infections occurred most often in the gastrointestinal, urinary, and respiratory systems, often occurring at more than one body site. The prevalence of bacterial infections in atopic dogs treated with cyclosporine is low and occurs most often in the skin. When given for immunosuppression, the prevalence of bacterial infections is higher and can affect one or more body systems.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33299244/