Peer-reviewed veterinary case report
Preventing Babesia canis in dogs with fipronil, amitraz
By Jongejan, Frans et al.·Published in Veterinary parasitology·2011·Faculty of Veterinary Medicine, Netherlands·View original on PubMed →
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Original publication title: The prevention of transmission of Babesia canis canis by Dermacentor reticulatus ticks to dogs using a novel combination of fipronil, amitraz and (S)-methoprene.
- Species:
- dog
Plain-English summary
A group of dogs was treated with a new spot-on treatment called CERTIFECT, which combines fipronil, amitraz, and (S)-methoprene, to prevent a tick-borne disease called babesiosis caused by Babesia canis canis. The dogs received the treatment at different intervals before being exposed to ticks known to carry the disease. While all untreated dogs developed symptoms of the illness, the majority of the treated dogs showed no signs of infection for 42 days after being infested. This suggests that using CERTIFECT can effectively protect dogs from getting sick from these ticks.
People also search for: dog tick prevention · babesiosis in dogs · CERTIFECT for dogs · how to prevent ticks on dogs
Abstract
Four groups of seven dogs were treated topically with a novel combination of fipronil, amitraz and (S)-methoprene in a spot-on formulation (CERTIFECT™, Merial Limited, GA, USA) on 28, 21, 14 and 7 days prior to tick infestation, respectively and acaricidal efficacy and transmission blocking compared with an untreated control group (seven dogs). All dogs were infested with adult Dermacentor reticulatus ticks harbouring Babesia canis canis. Babesia canis canis was transmitted by D. reticulatus to all seven untreated control dogs, confirmed following demonstration of clinical signs, by the detection of B. canis parasites in thin blood smears and B. canis canis PCR-RLB DNA assay on blood and the development of B. canis canis antibody titres by 14-21 days after tick infestation. The majority of treated dogs remained sero-negative for 42 days after infestation. Therefore, the treatment of dogs with CERTIFECT applied up to 28 days prior to infestation with D. reticulatus harbouring B. canis canis, successfully prevented the development of clinical signs of canine babesiosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21777737/