Peer-reviewed veterinary case report
Survival outlook for dogs with grade 2 mast cell tumors and lymph
By Baginski, Heather et al.·Published in Journal of the American Animal Hospital Association·2014·Surgery Department·View original on PubMed →
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Original publication title: The prognostic value of lymph node metastasis with grade 2 MCTs in dogs: 55 cases (2001-2010).
- Species:
- dog
Plain-English summary
A group of dogs with grade 2 skin tumors called mast cell tumors (MCTs) were treated with surgery to remove the main tumor. Some of these dogs had cancer spread to their lymph nodes, which was confirmed through tests. Surprisingly, having cancer in the lymph nodes didn't seem to affect how long the dogs lived. However, dogs that had their affected lymph nodes removed tended to live longer. This suggests that while lymph node spread isn't a major concern for survival, removing those nodes can help improve outcomes.
People also search for: dog mast cell tumor treatment · lymph node cancer in dogs · grade 2 MCT prognosis
Abstract
This study evaluates a series of dogs diagnosed with grade 2 cutaneous mast cell tumors (MCTs) with concurrent lymph node (LN) metastasis. All dogs had surgical excision of the primary tumor. The presence of metastasis was confirmed with either histopathology (n = 35) or cytology (n = 20). There was no significant difference in survival times (STs) between dogs with and without LN metastasis. Median survival time (MST) was not reached at 65.9 mo. LN palpation was a poor predictor of metastasis (sensitivity, .71; specificity, .54). Tumor location was the only prognostic factor for survival in this series of dogs. ST was greater for dogs that had removal of their metastatic LN. This study suggests that in dogs with grade 2 MCTs, outcome may not be affected by the presence of LN metastasis; however, removal of the metastatic LN may prolong survival.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24446400/