The Prolapse Quality of Life Questionnaire Can Serve as an Assessment Tool for Urinary Storage Conditions in Patients With Pelvic Organ Prolapse Undergoing Transvaginal Mesh Surgery.

Abstract

<h4>Aim</h4>The Prolapse Quality-of-Life Questionnaire (P-QOL) is a validated tool for assessing symptom severity and treatment outcomes in patients with pelvic organ prolapse (POP). This study investigates whether the total score of selected P-QOL component questions may serve as a surrogate marker for the Overactive Bladder Symptom Score (OABSS) and the International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF) in patients with POP undergoing transvaginal mesh surgery (TVM).<h4>Methods</h4>The study enrolled 148 patients who underwent TVM at our institution between September 2014 and March 2024. Correlations between the total score of selected P-QOL component questions and the OABSS or ICIQ-SF score were assessed using Spearman's rank correlation coefficient. The Kruskal-Wallis test compared P-QOL scores between OABSS ≥ 3 and ≤ 2 groups, and ICIQ-SF ≥ 6 and ≤ 5 groups at pre-operation and at 3, 6, and 12 months postoperatively.<h4>Results</h4>Significant correlations were observed between the total score of selected P-QOL component questions and the OABSS or ICIQ-SF score both preoperatively and postoperatively. Box plot analyses showed significant differences in P-QOL scores between the OABSS ≥ 3 and ≤ 2 groups and the ICIQ-SF ≥ 6 and ≤ 5 groups at all time points. Additionally, post-void residual urine volume, P-QOL scores, and OABSS and ICIQ-SF scores significantly decreased at 3, 6, and 12 months postoperatively compared with preoperative values.<h4>Conclusions</h4>The P-QOL provides reliable information regarding urinary storage conditions both preoperatively and postoperatively, making it a potential utility in reflecting urinary storage symptoms instead of the OABSS and ICIQ-SF for evaluating urinary storage symptoms in patients with POP.