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Peer-reviewed veterinary case report

The Relationship Between Periodontal Infection and Systemic and Distant Organ Disease in Dogs.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2022
Authors:
Harvey, Colin
Affiliation:
School of Veterinary Medicine · United States
Species:
dog

Abstract

Infection in the mouth causes systemic and distant organ changes in dogs. This article summarizes the information available. Reported changes include an increase in liver-generated acute-phase proteins in response to the infectious insult to the body and evidence of microscopic changes in renal, hepatic, and cardiac tissues. Treatment of periodontal infection results in a decrease in the acute-phase protein concentration, which supports the hypothesis that a cause-and-effect relationship exists between periodontal infection and distant organ changes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/34838247/