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Peer-reviewed veterinary case report

Safety of fast allergy shots for dogs with itchy skin in 230 cases

By Weitzer, Tamara & Mueller, Ralf·Published in Veterinary Dermatology·2023·Center for Clinical Veterinary Medicine LMU Munich Munich Germany, Germany·View original on Crossref

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Original publication title: The safety of rush immunotherapy in the management of canine atopic dermatitis—230 cases

Species:
dog

Plain-English summary

A group of 230 dogs with atopic dermatitis (a skin allergy) underwent a fast-track treatment called rush immunotherapy to help reduce their symptoms more quickly. During the treatment, only 6 dogs experienced mild side effects, such as vomiting or diarrhea, and one had a slight fever, but all these issues were temporary and resolved on their own. Overall, the study found that rush immunotherapy is a safe option for dogs, allowing them to reach their maintenance dose faster with minimal adverse effects.

People also search for: dog skin allergy treatment · rush immunotherapy for dogs · dog vomiting after allergy shot

Abstract

AbstractBackgroundThe duration of the induction phase of allergen‐specific immunotherapy conventionally is a period of several weeks, during which the volume of an allergen solution, administered by injection, is gradually increased until the maintenance dose is reached. In rush immunotherapy (RIT), the induction period is abbreviated to achieve a faster improvement in clinical signs of atopic dermatitis (AD) compared to conventional immunotherapy.ObjectiveThe aim of this retrospective study was to evaluate the safety of RIT in 230 dogs with AD and report any adverse effects (AE).AnimalsTwo hundred thirty client‐owned dogs.Materials and MethodsMedical records of dogs receiving RIT between 2012 and 2021 were analysed and observed AE were investigated. All dogs underwent RIT following a protocol of subcutaneous allergen extract injections, given hourly with an incrementally increasing volume from 0.1 to 1.0 mL.ResultsAdverse effects were documented in 6 of 230 (2.6%) dogs. Five of these dogs (2.2%) showed mild gastrointestinal signs (1 of 5 vomiting, 4 of 5 diarrhoea) and one patient an increase in body temperature by 1.5°C. These occurred at different stages of the RIT protocol. All AE were graded as mild and self‐limiting.Conclusions and Clinical RelevanceBased on these data, supervised RIT in dogs appears to be a safe procedure to achieve the maintenance dose of allergen immunotherapy earlier with infrequent and mild AE.

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Original publication on Crossref: https://doi.org/10.1111/vde.13170