Peer-reviewed veterinary case report
The Study of Cognitive Functions of Rats with Experimental Alzheimer's Disease after Transplantation of Transduced Olfactory Ensheathing Cells Expressing Nerve Growth Factor.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2025
- Authors:
- Karsuntseva, E K et al.
- Affiliation:
- V. Serbsky National Medical Research Centre for Psychiatry and Narcology
- Species:
- rodent
Abstract
We evaluated the efficiency of transplantation of a gene-cell construct based on olfactory ensheathing cells expressing neurotrophic NGF in female Wistar rats with an experimental model of Alzheimer's disease. NGF improved long-term memory and learning ability in the passive avoidance test at week 3 after cell transplantation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/40682644/