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Peer-reviewed veterinary case report

The treatment of Filaroides osleri infestation with albendazole.

Journal:
Journal of the South African Veterinary Association
Year:
1980
Authors:
van Heerden, J & Petrick, S W
Species:
dog

Plain-English summary

A dog with a Filaroides osleri infestation, which is a type of parasitic infection affecting the lungs, was treated with albendazole, a medication used to kill parasites. The dog received the medication daily for 55 days, and after 30 days, the signs of illness went away. However, some small nodules remained in the left bronchus (a part of the airway) even 373 days after starting treatment. The treatment also changed the dog's blood cell counts, increasing lymphocytes (a type of white blood cell) and decreasing neutrophils (another type of white blood cell). Overall, the treatment was effective in resolving the clinical signs of the disease, but some nodules persisted.

Abstract

A dog infested with Filaroides osleri was dosed with albendazole at 9,5 mg/kg every day for 55 days. Clinical signs of disease disappeared after 30 days but a few nodules were still present in the left bronchus 373 days after the onset of treatment. The anthelmintic caused an increase in lymphocyte and decrease in neutrophil count.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/7241501/