Peer-reviewed veterinary case report
The UK Veterinary Immunological Toolbox Website: promoting vaccine research by facilitating communication and removing reagent barriers.
- Journal:
- Immunology
- Year:
- 2020
- Authors:
- Mwangi, William et al.
- Affiliation:
- The Pirbright Institute · United Kingdom
Plain-English summary
Researchers are working to improve vaccines and understand how animals respond to diseases by using various animal models, especially livestock. To support this research, a new website has been created that provides access to important tools and information about veterinary immunology, which is the study of how animals' immune systems work. This site aims to help researchers and veterinarians by making it easier to find and use the right materials needed for their studies. The success of this project depends on the involvement of the community to keep adding valuable information. Overall, the goal is to make this website a key resource for anyone working with animal health and vaccines.
Abstract
Using the best animal models to study immune responses against specific pathogens or vaccines can dramatically accelerate our understanding. Veterinary species are well studied, particularly livestock, to reduce their disease burden. They have also proven to be powerful models, especially for zoonotic pathogens and novel vaccination strategies. A prerequisite for any model selection is having the right quality and range of species-specific immunological reagents. To help promote the widest possible use of veterinary species, an open access website (https://www.immunologicaltoolbox.co.uk) has been created as a central community annotated hub for veterinary immunological reagents. The website is also the portal into services offered by the UK Immunological Toolbox project that includes antibody generation, sequencing and recombinant expression. The funding for this effort is linked into sustainable sources, but ultimate success relies on community engagement to continually increase the quality and quantity of information. It is hoped that as more users and reagent owners engage, it will become an essential resource for researchers, veterinarians and clinicians alike by removing barriers that prevent the use of the most informative animal models.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32548865/