Peer-reviewed veterinary case report
Treatment of supraspinatus tendon injury in 55 dogs with stem cells
By Canapp, Sherman O et al.·Published in Frontiers in veterinary science·2016·Veterinary Orthopedic and Sports Medicine, United States·View original on PubMed →
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Original publication title: The Use of Adipose-Derived Progenitor Cells and Platelet-Rich Plasma Combination for the Treatment of Supraspinatus Tendinopathy in 55 Dogs: A Retrospective Study.
- Species:
- dog
Plain-English summary
A group of 55 dogs with shoulder pain due to supraspinatus tendinopathy (a tendon issue) received a treatment combining fat-derived stem cells and platelet-rich plasma. After the treatment, most dogs showed significant improvement in their ability to walk and use the affected leg, with 88% having no noticeable difference between the injured and healthy limb after 90 days. Additionally, ultrasound scans revealed a reduction in tendon size and better fiber structure in the treated tendons. This suggests that this combination therapy could be an effective option for dogs suffering from this condition.
People also search for: dog shoulder pain treatment · supraspinatus tendinopathy in dogs · stem cell therapy for dogs
Abstract
OBJECTIVE: To report clinical findings and outcomes for 55 dogs with supraspinatus tendinopathy (ST) treated with adipose-derived progenitor cells and platelet-rich plasma (ADPC-PRP) therapy. METHODS: Medical records of client-owned dogs diagnosed with ST that were treated with ADPC-PRP combination therapy were reviewed from 2006 to 2013. Data collected included signalment, medical history, limb involvement, prior treatments, physical and orthopedic examination, objective temporospatial gait analysis findings, diagnostic imaging results (radiography, magnetic resonance imaging, musculoskeletal ultrasonography), arthroscopy findings, and outcome. RESULTS: Following ultrasound-guided injection of ADPC-PRP, objective gait analysis was available on 25 of the 55 dogs at 90 days post ADPC-PRP therapy. Following treatment, a significant increase in total pressure index percentage (TPI%) was noted in the injured (treated) forelimb at 90 days post treatment (p = 0.036). At 90 days following treatment, 88% of cases had no significant difference in TPI% of the injured limb to the contralateral limb. The remaining 12% of cases had significantly improved (p = 0.036). Bilateral shoulder diagnostic musculoskeletal ultrasound revealed a significant reduction in tendon size (CSA) in the treated tendon at 90 days following treatment when compared to the initial CSA (p = 0.005). All cases showed significant improvement in fiber pattern of the affected supraspinatus tendon by the ultrasound shoulder pathology rating scale. CLINICAL RELEVANCE: These findings suggest that ADPC-PRP therapy should be considered for dogs with ST.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27668218/