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Peer-reviewed veterinary case report

Enalapril treatment for cats with thickened heart muscle disease

By Rush, J E et al.·Published in Journal of the American Animal Hospital Association·1998·Department of Medicine, United States·View original on PubMed

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Original publication title: The use of enalapril in the treatment of feline hypertrophic cardiomyopathy.

Species:
cat

Plain-English summary

A group of 19 cats with hypertrophic cardiomyopathy (HCM), a condition that can lead to heart failure, were treated with a medication called enalapril. At the start, 11 of these cats were experiencing congestive heart failure, but after three to six months of treatment, only one cat remained in heart failure. The cats showed significant improvements in heart size and function without any negative effects on their blood pressure or kidney health. While enalapril appears to be safe and may help some cats with HCM, more research is needed to confirm its effectiveness.

People also search for: cat heart disease treatment · feline hypertrophic cardiomyopathy medication · enalapril for cats heart failure

Abstract

The clinical response to enalapril in 19 cats with hypertrophic cardiomyopathy (HCM) was evaluated retrospectively. Eleven cats were in congestive heart failure (CHF) at the time enalapril was prescribed, while only one cat was in CHF when the cats were reexamined three-to-six months later. Significant changes in cardiac dimensions were identified echocardiographically. No adverse effects on blood pressure, serum creatinine, or potassium were noted. Although the preliminary data suggests that enalapril is well tolerated and may contribute to some improvements in cats with HCM, controlled, prospective studies are needed to prove the efficacy of enalapril in this disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9527429/