Peer-reviewed veterinary case report
Treatment of vasopressor leakage injuries in 3 dogs using terbutaline
By Lathroum, Chele N et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2024·Department of Medical Sciences, United States·View original on PubMed →
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Original publication title: The use of injectable subcutaneous terbutaline and topical nitroglycerin ointment in the treatment of peripheral vasopressor extravasation in 3 dogs.
- Species:
- dog
Plain-English summary
Three dogs experienced tissue damage due to a complication called vasopressor extravasation, which occurs when medication leaks out of blood vessels. The dogs were treated with a combination of injectable terbutaline and topical nitroglycerin ointment, which helped manage the injury. This approach is an alternative to the standard treatment that is often hard to get for pets. The dogs showed improvement with this treatment, helping to reduce the damage caused by the medication leak.
People also search for: dog tissue injury treatment · vasopressor extravasation in dogs · terbutaline for dogs · nitroglycerin ointment for pets
Abstract
OBJECTIVE: To describe the clinical course and treatment of 3 dogs with peripheral vasopressor extravasation. CASE SERIES SUMMARY: Although vasopressor extravasation (VE) is a well-documented complication in human medicine, literature describing VE and its management in veterinary patients is sparse. VE increases patient morbidity by causing local tissue injury and necrosis. The gold standard treatment for VE, phentolamine, has been periodically limited in supply in human medicine and is not consistently available for use in veterinary medicine. An alternative protocol proposed for use in people with VE combines topical nitroglycerin application with subcutaneous terbutaline infiltration. In this report, a treatment protocol utilizing these therapies was used to treat 3 dogs with VE and secondary tissue injury. NEW OR UNIQUE INFORMATION PROVIDED: This report describes 3 cases of VE-induced tissue injury in dogs. In addition, this report describes the use of perivascular terbutaline infiltration and topical nitroglycerin application as therapeutic management for VE in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39031632/