Peer-reviewed veterinary case report
Oral cyclosporin for treating skin problems in cats
By Vercelli, A et al.·Published in Veterinary dermatology·2006·Ambulatorio Veterinario Associato, Italy·View original on PubMed →
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Original publication title: The use of oral cyclosporin to treat feline dermatoses: a retrospective analysis of 23 cases.
- Species:
- cat
Plain-English summary
A group of 23 cats with various skin issues, including eosinophilic granulomas and severe itching, were treated with an oral medication called cyclosporin. After monitoring their progress over at least six months, all cats with eosinophilic conditions and those with idiopathic itching showed complete improvement and were able to continue treatment on alternate days. For the cats with plasmacytic stomatitis, half went into remission, while the others showed good improvement. Overall, cyclosporin was effective and safe for treating these skin problems in cats.
People also search for: cat skin problems treatment · eosinophilic granuloma in cats · cyclosporin for cat itching
Abstract
Limited information is available regarding the use of cyclosporin A (CsA) for the treatment of feline dermatoses. The aim of this retrospective study was therefore to describe the efficacy of CsA for the therapy of eosinophilic granuloma (EG), eosinophilic plaque, indolent ulcer, linear granulomas, idiopathic pruritus and stomatitis. A computer search for feline dermatological cases treated with CsA between 1999 and 2004 was performed. Based on history, clinical signs and laboratory diagnostic tests, it was then possible to divide cases into three groups and to select 23 cats. Seven cats had one or more of the following conditions: EG, eosinophilic plaque, indolent ulcer and/or linear granuloma (group A); eight cats had idiopathic pruritus (group B) and eight cats had plasmacytic stomatitis (group C). Doses ranged from 5.8 to 13.3 mg kg(-1) oral CsA. All cats were monitored, with complete serum blood analysis and physical examination, monthly for a minimum of 6 months. Response to therapy was scored (severity of lesions and pruritus) with a 0-10 visual analogue scale at each visit (day 0, day, 30, day 60, day 90). All cats in groups A and B were cured and were maintained on alternate day therapy. In group C, 4/8 patients went into remission, while remaining cats have a fair to good improvement. Routine haematological and biochemical examination failed to reveal abnormalities related to CsA administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16674736/