Peer-reviewed veterinary case report
Hair loss in Alaskan malamutes treated with trilostane
By Leone, F et al.·Published in Journal of the American Animal Hospital Association·2005·Clinica Veterinaria Adriatica, Italy·View original on PubMed →
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Original publication title: The use of trilostane for the treatment of alopecia X in Alaskan malamutes.
- Species:
- dog
Plain-English summary
Three Alaskan malamutes were brought in for hair loss and had slightly high levels of a hormone after a specific test. The veterinarian treated them with a medication called trilostane, which helps reduce hormone production. After 4 to 6 months of treatment, all three dogs experienced complete hair regrowth, and there were no side effects from the medication. This treatment proved effective for their condition.
People also search for: Alaskan malamute hair loss treatment · trilostane for dogs · dog hormone imbalance symptoms
Abstract
Three Alaskan malamutes with hair loss and slightly elevated blood concentrations of 17-hydroxyprogesterone after stimulation with adrenocorticotropic hormone (ACTH) were treated with trilostane. Trilostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase, was given twice daily at a dose of 3.0 to 3.6 mg/kg per day orally for 4 to 6 months. Routine ACTH stimulation tests were performed over 8 months to evaluate the degree of adrenal function suppression. Treatment with trilostane led to complete hair regrowth in all three dogs within 6 months. No adverse effects associated with trilostane were recognized.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16141187/