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Peer-reviewed veterinary case report

Theileria apicoplast as a target for chemotherapy.

Journal:
Antimicrobial agents and chemotherapy
Year:
2009
Authors:
Lizundia, Regina et al.
Affiliation:
D&#xe9 · France

Abstract

Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets. Putative inhibitors of these targets were screened, and we identified antiproliferative compounds that merit further characterization.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19075064/