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Peer-reviewed veterinary case report

Therapeutic effects of beta-thujaplicin eardrops on canine Malassezia-related otitis externa.

Journal:
The Journal of veterinary medical science
Year:
2006
Authors:
Nakano, Yasuyuki et al.
Affiliation:
Department of Veterinary Clinical Science · Japan
Species:
dog

Abstract

An eardrop solution of beta-thujaplicin was examined for therapeutic effects on canine Malassezia-related otitis externa. Half to one ml of beta-thujaplicin solution of 100 microg/ml including DMSO 2% was injected everyday into both external ear canals of 31 cases for test-of-cure agreement. Fifteen score phases were established from the symptoms and cerumen smear biopsy findings, and score changes were recorded at least once a week. The means of the second and the third inspection day scores decreased significantly more than the previous value of each. In addition, the numbers of yeast-like organisms clearly decreased. These results suggest that beta-thujaplicin eardrops are effective for Malassezia-related otitis externa in dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16679729/